Roles

$212,000/hour - $333,190/hour

Cambridge, Massachusetts

Hybrid

Leader

Head of R&D Global Capability Centers (Vice President) - Transformational R&D Leadership (BOSTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Purpose

Leveraging a proven track record of leading at least 3 discovery programs to clinic, The Global Therapeutic Research Lead (GTRL) is a pipeline critical strategic leader responsible for driving Research projects to the clinic. The individual will sit on the Gastroenterology and Inflammation Drug Discovery Unit (GI DDU) Leadership Team.
Leader for at least one or more of Takeda’s top priority projects with substantial clinical and commercial potential with a clear accelerated path to the clinic.
You will provide mentorship to team members to elevate enterprise thinking and capabilities of our drug discovery talent across the global Research function.
As project lead, the GTRL builds a connected view of the project within the Gastroenterology and Inflammation TA strategy and treatment paradigm and can represent all core expertise at depth and align with stakeholders and sponsors across the organization including Research, Clinical Development and Commercial stakeholders and executive level governance committees.
The GTRL will be responsible for creating the medicine vision, early asset strategy and managing multiple external partnerships that accelerate delivery of the project.
The GTRL will establish smart, fast, and critical path minded practices for groups, including integrating new strategies and competitive industry ways of working.
The GTRL will advise on the continuous infusion of new Research projects aligned to strategy to generate a sustainable Research Engine generating a steady flow of high-quality INDs every year.

Accountabilities

Lead and manage one or more ‘Top 10’ drug discovery projects, overseeing the entire drug discovery process from target identification to preclinical development. (Top 10 projects are well validated targets that are focused on strategically aligned modalities with substantial clinical and commercial potential)
Responsible for the articulation and ownership of the project strategy, developed in partnership with internal stakeholders.
Contribute to strategy for future portfolio investment, particularly within the Inflammation and Immunology area including advising on which projects should be Top 10 projects.
Evaluate and prioritize potential drug candidates based on scientific, medical, and commercial considerations.
Represent all core expertise for the project.
Partner with Clinical and Translational teams to refine asset strategy.
Ensure alignment to the therapeutic area strategy (i.e., Clinical Development).
Understand and align with the commercial team for asset commercial value within the TA.
Provide guidance and mentorship to global project team members, stimulating enterprise thinking and fostering their professional growth and development.
Mentor future and more junior project leads and elevate drug discovery capability across Research.
Collaborate with cross-functional teams and partners (e.g., DMPK, Pharmaceutical Sciences) within and outside Takeda to drive project delivery.
Pipeline and enterprise impact through effective partnering with multiple internal and external collaborators.
Provide strategic, process, and operational leadership for successful Top 10 Project delivery.
Foster a culture of innovation and scientific excellence within the matrixed drug discovery team, promoting collaboration, knowledge sharing, and continuous learning.
Become a world leading scientific expert in the projects you lead.
Oversee the design and execution of experiments, data analysis, and interpretation to enable decision-making and optimize drug discovery efforts.
Stay abreast of the latest advancements in drug discovery, emerging technologies, and industry trends, applying this knowledge to enhance drug discovery strategies.
Build and maintain relationships with key stakeholders, including academic institutions, research organizations, and industry partners inclusive of serving on joint external governance committees across the globe.
Represent Takeda externally for the Gastroenterology and Inflammation Drug Discovery Unit and play a key role in evaluating external opportunities, serving as an effective ambassador for Takeda’s global business development brand.

Education & Competencies (Technical and Behavioral):

PhD degree in a scientific discipline with 15+ years experience , orMS with 21+ years experience, or BS with 23+ years experience
Expected to have at least 10-12 years industry and relevant subject matter expertise within Immunology and Inflammation and at least 10-12 years global management experience, including working effectively with matrix teams.
Extensive experience in leading drug discovery teams and managing drug discovery/development projects, preferably in a pharmaceutical or biotechnology setting covering gastroenterology and inflammation.
Deep understanding of the drug discovery process, including target identification, hit-to-lead optimization, and preclinical development, anticipating, and removing roadblocks.
Proven track record of leading numerous projects, ideally 5+ projects, across discovery from target inception to Candidate Nomination or beyond.
Played a major role in 3+ INDs.
Has delivered clinical development assets, must include experience with biologics and preferably across multiple modalities.
Excellent and inclusive leadership with the ability to inspire and motivate diverse teams towards achieving ambitious goals.
Reputation as a proactive, solutions-oriented leader who engages relevant expertise no matter where it resides.
Strong business acumen and understanding of the pharmaceutical industry, including regulatory requirements and commercial considerations with relevant knowledge and expertise for specific modalities.
Exceptional communication and presentation skills, with the ability to effectively communicate complex scientific concepts to diverse audiences.
Proven ability to build and maintain collaborative relationships with internal and external stakeholders across a matrixed organization.
Strong problem-solving and decision-making abilities, with a focus on data-driven decision making.
Demonstrated success in building and managing strategic partnerships with academic institutions, research organizations, and industry collaborators.

ADDITIONAL INFORMATION

The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$212,000.00 - $333,190.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

$259,000/hour - $407,000/hour

Cambridge, Massachusetts

Hybrid

Leader

User Interface Development Specialist (LEXINGTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

About the role:

The Head of R&D Global Capability Centers (GCC) is a senior enterprise leadership role accountable for shaping, establishing, and scaling Takeda’s globally integrated, multi-hub R&D delivery model. The role serves as the single, cross‐R&D point of accountability for GCC strategy, operating model design, and execution, and acts as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership Team during hub establishment and early maturity phases.

Operating at an executive level, this leader partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs in Poland and India are established and fully integrated into Takeda R&D, delivering sustainable capabilities, talent pipelines, and long‐term enterprise value.

How you will contribute:

Takeda is seeking a senior R&D leader to own R&D’s Global Capability Center (GCC) vision, and lead and coordinate R&D GCC activities across the enterprise. This role is accountable for coordinating the establishment and scaling of R&D hub locations in Poland and India, aligned to a multi-hub, globally integrated R&D development model.

The role operates as the single, cross‐R&D point of accountability for GCC strategy, execution, and integration, and serves as the primary R&D interface to the Enterprise Transformation Office and R&D Leadership during hub stand‐up and early maturity phases.

This position reports into the Head of R&D Operational Excellence and partners closely with R&D functions, Therapeutic Areas, and enterprise stakeholders to ensure that global hubs deliver both near‐term value and long‐term capability building. This role requires significant cross functional leadership.

Strategic Context:

This role supports Takeda’s evolution toward a globally integrated, multi‐hub R&D model that:

Establishes Cambridge, MA, Poland, and Bangaluru, India as interconnected R&D hubs
Focus on capability and talent development
Enables hybrid Global Program Team (GPT) execution across hubs
Requires strong central leadership to coordinate governance, integration, and change management

Key Responsibilities:

Enterprise & R&D Leadership:

Serve as the R&D‐wide GCC Lead with accountability for strategy, execution, and evolution
Act as primary R&D counterpart to the Enterprise Transformation Office and R&D Leadership
Representing GCC strategy with senior R&D and enterprise governance forums

GCC Strategy & Operating Model:

Define the multi‐year GCC vision and roadmap
Design and implement the multi‐hub operating model
Ensure alignment with R&D functional strategies

Hub Establishment & Scale‐Up (Poland & India):

Lead R&D input into hub stand‐up
Partner with enterprise teams on infrastructure, talent, and change
Enable phased capability scaling

Cross‐Functional Coordination:

Coordinate across R&D functions and Therapeutic Areas
Resolve cross‐functional dependencies
Ensure clear accountability

Talent, Capability & Culture:

Shape leadership and talent models
Support sustainable talent pipelines
Promote Takeda values

Minimum Requirements/Qualifications:

Required:

15+ years leadership experience in life sciences R&D
Experience across multiple R&D functions
Large‐scale transformation leadership
Global Capability Center operating experience

Preferred:

GCC or global delivery hub experience
Hybrid operating model exposure
Digital, data, or AI‐enabled R&D transformation
Advanced degree

Travel: 30% travel required

This position is currently classified as hybrid in accordance with Takeda’s Hybrid and Remote Work policy.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$259,000.00 - $407,000.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

YesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

$154,400/hour - $242,550/hour

Lexington, Massachusetts

In office

Senior - Leader

Head of R&D Global Capability Centers (Vice President) (BOSTON)

By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.

Job Description

Objective:

Human Factors Engineering (HFE) Lead - Associate Engineering Fellow (AEF) is responsible for Human Centered Design of Medical Devices and Combination Products. The HFE Lead - AEF will be integral to design and development of product user interface including hardware, software, packaging, labeling, and instruction material to support safe and effective use of the product for the intended use by the intended users in the anticipated use environment.

The HFE Lead responsibilities include but are not limited to:

Leading and executing Human Factors strategy in compliance with regional regulatory guidance.
Driving and overseeing User Research strategy in compliance with Quality Management System.
Developing Human Factors Product and System level requirements in alignment with Target Product Profile.
Conducting exploratory research to gather user insights and design trends and evaluate user interface concepts.
Translating user needs into user experience and interface requirements and specifications.
Designing and executing Human Factors studies to iteratively evaluating product user interface – including hardware, software, packaging, instructional material, and training.
Conducting Task and Known Use Problem Analyses.
Performing use-safety engineering through Use-related Risk Analysis.
Developing Human Factors Validation Protocols and Reports.
Managing Human Factors, Industrial Design, and User Research vendors.
Supporting regulatory Human Factors Information Requests.
Developing Human Factors Summary Reports in compliance with FDA guidance.
Developing Usability Engineering Files in compliance with IEC and ISO standards.
Leading development to Human Factors standard operating procedures and templates development.
Applying functional knowledge of applicable guidance, regulations, standards, and industry best practices to medical device and combination product design and development process.
Preparing documentation to support medical device and combination product development activities including design controls.
Collaborating with cross functional team members from mechanical, software, clinical, regulatory, and quality engineering disciplines.
Qualifying and managing Human Factors vendors.
Supporting internal and external quality audits.
Communicating with internal and external key stakeholders.
Mentoring Human Factors Engineering Leads.

Education & Qualifications:

Doctorate degree and 7+ years of Human Factors Engineering, Biomedical Engineering, Industrial Engineering, other relevant degrees in device design or biotech industry.
OR, Master’s degree and 13+ years of Human Factors Engineering, Biomedical Engineering, Industrial Engineering, other relevant degrees in device design or biotech industry.
OR, Bachelor’s degree and 15+ years of Human Factors Engineering, Biomedical Engineering, Industrial Engineering, other relevant degrees in device design or biotech industry

Physical Health Requirements:

While the role of a Human Factors Engineering Lead primarily involves cognitive and analytical tasks, good physical health is essential. Engineers may need to visit manufacturing sites or conduct user testing in clinical environments, which might involve walking, standing, or other physical activities.
Depending on the role and specific responsibilities, a Human Factors Engineering Lead may need to travel to clinical sites, supplier facilities, or other locations for research and testing purposes.

Travel Requirements:

This position may require up to 20% yearly travel, including domestic and international.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Lexington, MA

U.S. Base Salary Range:

$154,400.00 - $242,550.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Lexington, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

YesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

$259,000/hour - $407,000/hour

Cambridge, Massachusetts

Hybrid

Leader